Cytotoxic Activity and Quantitative Structure Activity Relationships of Arylpropyl Sulfonamides

B13 is a ceramide analogue and apoptosis inducer with potent cytotoxic activity. A series of arylpropyl sulfonamide analogues of B13 were evaluated for their cytotoxicity using MTT assays in prostate cancer PC-3 and leukemia HL-60 cell lines. Some compounds (4, 9, 13, 14, 15, and 20) showed stronger...

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Библиографические подробности
Главные авторы: Hwang, Yu Jin, Park, Sang Min, Yim, Chul Bu, Im, Chaeuk
Формат: Artigo
Язык:Inglês
Опубликовано: The Korean Physiological Society and The Korean Society of Pharmacology 2013
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682085/
https://ncbi.nlm.nih.gov/pubmed/23776401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2013.17.3.237
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