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Cytotoxic Activity and Three-Dimensional Quantitative Structure Activity Relationship of 2-Aryl-1,8-naphthyridin-4-ones

A series of substituted 2-arylnaphthyridin-4-one analogues, which were previously synthesized in our laboratory, were evaluated for their in vitro cytotoxic activity against human lung cancer A549 and human renal cancer Caki-2 cells using MTT assay. Some compounds (11, 12, and 13) showed stronger cy...

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Autors principals: Kim, Yong Jin, Kim, Eun Ae, Chung, Mi Lyang, Im, Chaeuk
Format: Artigo
Idioma:Inglês
Publicat: The Korean Physiological Society and The Korean Society of Pharmacology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802314/
https://ncbi.nlm.nih.gov/pubmed/20054500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2009.13.6.511
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