Decline in Titers of Anti-Idiotypic Antibodies Specific to Autoantibodies to GAD65 (GAD65Ab) Precedes Development of GAD65Ab and Type 1 Diabetes

The humoral Idiotypic Network consisting of antibodies and their anti-idiotypic antibodies (anti-Id) can be temporarily upset by antigen exposure. In the healthy immune response the original equilibrium is eventually restored through counter-regulatory mechanisms. In certain autoimmune diseases howe...

Full description

Saved in:
Bibliographic Details
Main Authors: Larsson, Helena Elding, Jönsson, Ida, Lernmark, Åke, Ivarsson, Sten, Radtke, Jared R., Hampe, Christiane S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681789/
https://ncbi.nlm.nih.gov/pubmed/23785410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065173
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items