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Incidence and Risk of Treatment-Related Mortality with mTOR Inhibitors Everolimus and Temsirolimus in Cancer Patients: A Meta-Analysis

BACKGROUND: Two novel mammalian targets of rapamycin (mTOR) inhibitors everolimus and temsirolimus are now approved by regulatory agencies and have been widely investigated among various types of solid tumors, but the risk of fatal adverse events (FAEs) with these drugs is not well defined. METHODS:...

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Detalhes bibliográficos
Main Authors: Qi, Wei-Xiang, Huang, Yu-Jing, Yao, Yang, Shen, Zan, Min, Da-Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681778/
https://ncbi.nlm.nih.gov/pubmed/23785409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065166
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