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Identification of pVHL as a Novel Substrate for Aurora-A in Clear Cell Renal Cell Carcinoma (ccRCC)

Clear cell renal cell carcinoma (ccRCC) is the most common histological subtype of kidney cancer and is often characterized by mutations or deletions of the Von Hippel Lindau (VHL) tumour suppressor gene. Aurora gene family members are implicated in proper mitotic progression and spindle checkpoint...

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Autors principals: Martin, Benedicte, Chesnel, Franck, Delcros, Jean-Guy, Jouan, Florence, Couturier, Anne, Dugay, Frederic, Le Goff, Xavier, Patard, Jean-Jacques, Fergelot, Patricia, Vigneau, Cecile, Rioux-Leclerq, Nathalie, Arlot-Bonnemains, Yannick
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681765/
https://ncbi.nlm.nih.gov/pubmed/23785518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067071
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