Combination of DNA Prime – Adenovirus Boost Immunization with Entecavir Elicits Sustained Control of Chronic Hepatitis B in the Woodchuck Model

A potent therapeutic T-cell vaccine may be an alternative treatment of chronic hepatitis B virus (HBV) infection. Previously, we developed a DNA prime-adenovirus (AdV) boost vaccination protocol that could elicit strong and specific CD8(+) T-cell responses to woodchuck hepatitis virus (WHV) core ant...

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Main Authors: Kosinska, Anna D., Zhang, Ejuan, Johrden, Lena, Liu, Jia, Seiz, Pia L., Zhang, Xiaoyong, Ma, Zhiyong, Kemper, Thekla, Fiedler, Melanie, Glebe, Dieter, Wildner, Oliver, Dittmer, Ulf, Lu, Mengji, Roggendorf, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681757/
https://ncbi.nlm.nih.gov/pubmed/23785279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003391
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