Woodchuck Gamma Interferon Upregulates Major Histocompatibility Complex Class I Transcription but Is Unable To Deplete Woodchuck Hepatitis Virus Replication Intermediates and RNAs in Persistently Infected Woodchuck Primary Hepatocytes

Gamma interferon (IFN-γ) is an important mediator with multiple functions in the host defense against viral infection. IFN-γ, in concert with tumor necrosis factor alpha (TNF-α), leads to a remarkable reduction of intrahepatic replication intermediates and specific mRNAs of hepatitis B virus (HBV) b...

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Autores principales: Lu, Mengji, Lohrengel, Beate, Hilken, Gero, Kemper, Thekla, Roggendorf, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC135691/
https://ncbi.nlm.nih.gov/pubmed/11739671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.1.58-67.2002
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