Oxidative Stress and DNA Lesions: The Role of 8-Oxoguanine Lesions in Trypanosoma cruzi Cell Viability

The main consequence of oxidative stress is the formation of DNA lesions, which can result in genomic instability and lead to cell death. Guanine is the base that is most susceptible to oxidation, due to its low redox potential, and 8-oxoguanine (8-oxoG) is the most common lesion. These characterist...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Aguiar, Pedro H. N., Furtado, Carolina, Repolês, Bruno M., Ribeiro, Grazielle A., Mendes, Isabela C., Peloso, Eduardo F., Gadelha, Fernanda R., Macedo, Andrea M., Franco, Glória R., Pena, Sérgio D. J., Teixeira, Santuza M. R., Vieira, Leda Q., Guarneri, Alessandra A., Andrade, Luciana O., Machado, Carlos R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2013
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681716/
https://ncbi.nlm.nih.gov/pubmed/23785540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002279
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