Oxidative Stress and DNA Lesions: The Role of 8-Oxoguanine Lesions in Trypanosoma cruzi Cell Viability

The main consequence of oxidative stress is the formation of DNA lesions, which can result in genomic instability and lead to cell death. Guanine is the base that is most susceptible to oxidation, due to its low redox potential, and 8-oxoguanine (8-oxoG) is the most common lesion. These characterist...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Aguiar, Pedro H. N., Furtado, Carolina, Repolês, Bruno M., Ribeiro, Grazielle A., Mendes, Isabela C., Peloso, Eduardo F., Gadelha, Fernanda R., Macedo, Andrea M., Franco, Glória R., Pena, Sérgio D. J., Teixeira, Santuza M. R., Vieira, Leda Q., Guarneri, Alessandra A., Andrade, Luciana O., Machado, Carlos R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681716/
https://ncbi.nlm.nih.gov/pubmed/23785540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002279
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars