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Apical sorting of lysoGPI-anchored proteins occurs independent of association with detergent-resistant membranes but dependent on their N-glycosylation

Most glycosylphosphatidylinositol-anchored proteins (GPI-APs) are located at the apical surface of epithelial cells. The apical delivery of GPI-APs is believed to result from their association with lipid rafts. We find that overexpression of C-terminally tagged PGAP3 caused predominant production of...

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Detalhes bibliográficos
Main Authors: Castillon, Guillaume Alain, Michon, Laetitia, Watanabe, Reika
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681704/
https://ncbi.nlm.nih.gov/pubmed/23615438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-03-0160
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