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Detergent-insoluble GPI–anchored Proteins Are Apically Sorted in Fischer Rat Thyroid Cells, but Interference with Cholesterol or Sphingolipids Differentially Affects Detergent Insolubility and Apical Sorting

In contrast to Madin–Darby canine kidney cells, Fischer rat thyroid cells deliver the majority of endogenous glycosylphosphatidyl inositol (GPI)–anchored proteins to the basolateral surface. However, we report here that the GPI proteins Placental Alkaline Phosphatase (PLAP) and Neurotrophin Receptor...

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Библиографические подробности
Главные авторы: Lipardi, Concetta, Nitsch, Lucio, Zurzolo, Chiara
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2000
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC14791/
https://ncbi.nlm.nih.gov/pubmed/10679012
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