Activation of ADF/cofilin by phosphorylation-regulated Slingshot phosphatase is required for the meiotic spindle assembly in Xenopus laevis oocytes

We identify Xenopus ADF/cofilin (XAC) and its activator, Slingshot phosphatase (XSSH), as key regulators of actin dynamics essential for spindle microtubule assembly during Xenopus oocyte maturation. Phosphorylation of XSSH at multiple sites within the tail domain occurs just after germinal vesicle...

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Main Authors: Iwase, Shohei, Sato, Ryuhei, De Bock, Pieter-Jan, Gevaert, Kris, Fujiki, Saburo, Tawada, Toshinobu, Kuchitsu, Miyako, Yamagishi, Yuka, Ono, Shoichiro, Abe, Hiroshi
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2013
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681698/
https://ncbi.nlm.nih.gov/pubmed/23615437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-12-0851
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