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The Gene Desert Mammary Carcinoma Susceptibility Locus Mcs1a Regulates Nr2f1 Modifying Mammary Epithelial Cell Differentiation and Proliferation

Genome-wide association studies have revealed that many low-penetrance breast cancer susceptibility loci are located in non-protein coding genomic regions; however, few have been characterized. In a comparative genetics approach to model such loci in a rat breast cancer model, we previously identifi...

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Autori principali: Smits, Bart M. G., Haag, Jill D., Rissman, Anna I., Sharma, Deepak, Tran, Ann, Schoenborn, Alexi A., Baird, Rachael C., Peiffer, Dan S., Leinweber, David Q., Muelbl, Matthew J., Meilahn, Amanda L., Eichelberg, Mark R., Leng, Ning, Kendziorski, Christina, John, Manorama C., Powers, Patricia A., Alexander, Caroline M., Gould, Michael N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681674/
https://ncbi.nlm.nih.gov/pubmed/23785296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003549
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