Unsupervised Clustering of Subcellular Protein Expression Patterns in High-Throughput Microscopy Images Reveals Protein Complexes and Functional Relationships between Proteins

Protein subcellular localization has been systematically characterized in budding yeast using fluorescently tagged proteins. Based on the fluorescence microscopy images, subcellular localization of many proteins can be classified automatically using supervised machine learning approaches that have b...

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Detalhes bibliográficos
Main Authors: Handfield, Louis-François, Chong, Yolanda T., Simmons, Jibril, Andrews, Brenda J., Moses, Alan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681667/
https://ncbi.nlm.nih.gov/pubmed/23785265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003085
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