Towards better understanding of an industrial cell factory: investigating the feasibility of real-time metabolic flux analysis in Pichia pastoris

BACKGROUND: Novel analytical tools, which shorten the long and costly development cycles of biopharmaceuticals are essential. Metabolic flux analysis (MFA) shows great promise in improving our understanding of the metabolism of cell factories in bioreactors, but currently only provides information p...

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Detalhes bibliográficos
Main Authors: Fazenda, Mariana L, Dias, Joao ML, Harvey, Linda M, Nordon, Alison, Edrada-Ebel, Ruan, LittleJohn, David, McNeil, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681591/
https://ncbi.nlm.nih.gov/pubmed/23692918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-12-51
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