Lin28b Promotes Head and Neck Cancer Progression via Modulation of the Insulin-Like Growth Factor Survival Pathway

Lin28 is a developmentally regulated RNA binding protein which has recently emerged as key regulator in the biogenesis of the let-7 micro-RNA family. While the expression of Lin28b has been linked to advanced tumor stage, the precise molecular mechanism(s) by which Lin28b drives disease progression...

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Bibliographische Detailangaben
Hauptverfasser: Alajez, Nehad M., Shi, Wei, Wong, Dennis, Lenarduzzi, Michelle, Waldron, John, Weinreb, Ilan, Liu, Fei-Fei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2012
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681501/
https://ncbi.nlm.nih.gov/pubmed/23482325
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