Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples

BACKGROUND: Meta-analysis of case-control genome wide association studies (GWAS) for early onset and morbid obesity identified four variants in/near the PRL, PTER, MAF and NPC1 genes. OBJECTIVE: We aimed to validate association of these variants with obesity-related traits in population-based sample...

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Hlavní autoři: den Hoed, Marcel, Luan, Jian’an, Langenberg, Claudia, Cooper, Cyrus, Sayer, Avan Aihie, Jameson, Karen, Kumari, Meena, Kivimaki, Mika, Hingorani, Aroon D, Grøntved, Anders, Khaw, Kay-Tee, Ekelund, Ulf, Wareham, Nicholas J, Loos, Ruth JF
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680864/
https://ncbi.nlm.nih.gov/pubmed/22430306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2012.34
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