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Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study.

We have previously shown that multiple genetic loci identified by genome-wide association studies (GWAS) increase the susceptibility to obesity in a cumulative manner. It is, however, not known whether and to what extent this genetic susceptibility may be attenuated by a physically active lifestyle....

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Detalhes bibliográficos
Main Authors: Shengxu Li, Jing Hua Zhao, Jian'an Luan, Ulf Ekelund, Robert N Luben, Kay-Tee Khaw, Nicholas J Wareham, Ruth J F Loos
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2010-08-01
Colecção:PLoS Medicine
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20824172/pdf/?tool=EBI
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