Drosophila Polo regulates the spindle assembly checkpoint through Mps1-dependent BubR1 phosphorylation

Maintenance of genomic stability during eukaryotic cell division relies on the spindle assembly checkpoint (SAC) that prevents mitotic exit until all chromosomes are properly attached to the spindle. Polo is a mitotic kinase proposed to be involved in SAC function, but its role has remained elusive....

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Bibliographische Detailangaben
Hauptverfasser: Conde, Carlos, Osswald, Mariana, Barbosa, João, Moutinho-Santos, Tatiana, Pinheiro, Diana, Guimarães, Sofia, Matos, Irina, Maiato, Helder, Sunkel, Claudio E
Format: Artigo
Sprache:Inglês
Veröffentlicht: European Molecular Biology Organization 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680734/
https://ncbi.nlm.nih.gov/pubmed/23685359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.109
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