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DiBAC(4)(3) hits a “sweet spot” for the activation of arterial large-conductance Ca(2+)-activated potassium channels independently of the β(1)-subunit

The voltage-sensitive dye bis-(1,3-dibutylbarbituric acid)trimethine oxonol [DiBAC(4)(3)] has been reported as a novel large-conductance Ca(2+)-activated K(+) (BK) channel activator with selectivity for its β(1)- or β(4)-subunits. In arterial smooth muscle, BK channels are formed by a pore-forming α...

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Bibliografske podrobnosti
Main Authors: Scornik, Fabiana S., Bucciero, Ronald S., Wu, Yuesheng, Selga, Elisabet, Bosch Calero, Cristina, Brugada, Ramon, Pérez, Guillermo J.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680725/
https://ncbi.nlm.nih.gov/pubmed/23542916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00939.2012
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