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Upregulation of p21 activates the intrinsic apoptotic pathway in β-cells
Diabetes manifests from a loss in functional β-cell mass, which is regulated by a dynamic balance of various cellular processes, including β-cell growth, proliferation, and death as well as secretory function. The cell cycle machinery comprised of cyclins, kinases, and inhibitors regulates prolifera...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3680698/ https://ncbi.nlm.nih.gov/pubmed/23592481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00663.2012 |
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