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Using a novel coculture model to dissect the role of intramuscular lipid load on skeletal muscle insulin responsiveness under reduced estrogen conditions

Reductions in estrogen function lead to adiposity and peripheral insulin resistance. Significant metabolic changes have been found in adipocytes and skeletal muscle with disruptions in the estrogen-signaling axis; however, it is unclear if intercellular communication exists between these tissues. Th...

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Detalhes bibliográficos
Main Authors: Wohlers, Lindsay M., Powers, Brittany L., Chin, Eva R., Spangenburg, Espen E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680679/
https://ncbi.nlm.nih.gov/pubmed/23548610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00617.2012
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