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Immortalization by c-myc, H-ras, and Ela oncogenes induces differential cellular gene expression and growth factor responses.

Early-passage rat kidney cells were immortalized or rescued from senescence with three different oncogenes: viral promoter-driven c-myc, H-ras (Val-12), and adenovirus type 5 E1a. The normal c-myc and H-ras (Gly-12) were unable to immortalize cells under similar conditions. Quantitation of RNA in th...

詳細記述

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書誌詳細
出版年:Mol Cell Biol
主要な著者: Kelekar, A, Cole, M D
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 1987
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368057/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2963209/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.11.3899-3907.1987
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