Immortalization by c-myc, H-ras, and Ela oncogenes induces differential cellular gene expression and growth factor responses.
Early-passage rat kidney cells were immortalized or rescued from senescence with three different oncogenes: viral promoter-driven c-myc, H-ras (Val-12), and adenovirus type 5 E1a. The normal c-myc and H-ras (Gly-12) were unable to immortalize cells under similar conditions. Quantitation of RNA in th...
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | Mol Cell Biol |
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| Κύριοι συγγραφείς: | , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Taylor & Francis
1987
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368057/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2963209/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.11.3899-3907.1987 |
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