Advanced Glycation End Products Induce Peroxisome Proliferator-Activated Receptor γ Down-Regulation-Related Inflammatory Signals in Human Chondrocytes via Toll-Like Receptor-4 and Receptor for Advanced Glycation End Products

Accumulation of advanced glycation end products (AGEs) in joints is important in the development of cartilage destruction and damage in age-related osteoarthritis (OA). The aim of this study was to investigate the roles of peroxisome proliferator-activated receptor γ (PPARγ), toll-like receptor 4 (T...

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Main Authors: Chen, Ying Ju, Sheu, Meei Ling, Tsai, Keh Sung, Yang, Rong Sen, Liu, Shing Hwa
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680452/
https://ncbi.nlm.nih.gov/pubmed/23776688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066611
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