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Genetic Loci for Retinal Arteriolar Microcirculation

Narrow arterioles in the retina have been shown to predict hypertension as well as other vascular diseases, likely through an increase in the peripheral resistance of the microcirculatory flow. In this study, we performed a genome-wide association study in 18,722 unrelated individuals of European an...

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Hauptverfasser: Sim, Xueling, Jensen, Richard A., Ikram, M. Kamran, Cotch, Mary Frances, Li, Xiaohui, MacGregor, Stuart, Xie, Jing, Smith, Albert Vernon, Boerwinkle, Eric, Mitchell, Paul, Klein, Ronald, Klein, Barbara E. K., Glazer, Nicole L., Lumley, Thomas, McKnight, Barbara, Psaty, Bruce M., de Jong, Paulus T. V. M., Hofman, Albert, Rivadeneira, Fernando, Uitterlinden, Andre G., van Duijn, Cornelia M., Aspelund, Thor, Eiriksdottir, Gudny, Harris, Tamara B., Jonasson, Fridbert, Launer, Lenore J., Attia, John, Baird, Paul N., Harrap, Stephen, Holliday, Elizabeth G., Inouye, Michael, Rochtchina, Elena, Scott, Rodney J., Viswanathan, Ananth, Li, Guo, Smith, Nicholas L., Wiggins, Kerri L., Kuo, Jane Z., Taylor, Kent D., Hewitt, Alex W., Martin, Nicholas G., Montgomery, Grant W., Sun, Cong, Young, Terri L., Mackey, David A., van Zuydam, Natalie R., Doney, Alex S. F., Palmer, Colin N. A., Morris, Andrew D., Rotter, Jerome I., Tai, E. Shyong, Gudnason, Vilmundur, Vingerling, Johannes R., Siscovick, David S., Wang, Jie Jin, Wong, Tien Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680438/
https://ncbi.nlm.nih.gov/pubmed/23776548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065804
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