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Molecular Basis for the Dissociation Dynamics of Protein A-Immunoglobulin G1 Complex

Staphylococcus aureus protein A (SpA) is the most popular affinity ligand for immunoglobulin G1 (IgG1). However, the molecular basis for the dissociation dynamics of SpA-IgG1 complex is unclear. Herein, coarse-grained (CG) molecular dynamics (MD) simulations with the Martini force field were used to...

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Autori principali: Liu, Fu-Feng, Huang, Bo, Dong, Xiao-Yan, Sun, Yan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680412/
https://ncbi.nlm.nih.gov/pubmed/23776704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066935
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