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Temporal and spatial requirements of Smoothened in ventral midbrain neuronal development

BACKGROUND: Several studies have indicated that Sonic hedgehog (Shh) regulates the expansion of dopaminergic (DA) progenitors and the subsequent generation of mature DA neurons. This prevailing view has been based primarily on in vitro culture results, and the exact in vivo function of Shh signaling...

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Detalhes bibliográficos
Main Authors: Tang, Mianzhi, Luo, Sarah X, Tang, Vivian, Huang, Eric J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680293/
https://ncbi.nlm.nih.gov/pubmed/23618354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8104-8-8
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