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Association of genes of protease-antiprotease balance pathway to lung function and emphysema subtypes

BACKGROUND: The imbalance between proteases and antiproteases has been proposed to participate to the pathogenesis of chronic obstructive pulmonary disease (COPD) and emphysema. Gene level variation in different metalloproteinases, metalloproteinase inhibitors, and cytokines affecting them may contr...

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Autori principali: Kukkonen, Mari K, Tiili, Emmi, Vehmas, Tapio, Oksa, Panu, Piirilä, Päivi, Hirvonen, Ari
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680142/
https://ncbi.nlm.nih.gov/pubmed/23734748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-13-36
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