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Association of genes of protease-antiprotease balance pathway to lung function and emphysema subtypes

BACKGROUND: The imbalance between proteases and antiproteases has been proposed to participate to the pathogenesis of chronic obstructive pulmonary disease (COPD) and emphysema. Gene level variation in different metalloproteinases, metalloproteinase inhibitors, and cytokines affecting them may contr...

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Detalhes bibliográficos
Main Authors: Kukkonen, Mari K, Tiili, Emmi, Vehmas, Tapio, Oksa, Panu, Piirilä, Päivi, Hirvonen, Ari
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680142/
https://ncbi.nlm.nih.gov/pubmed/23734748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-13-36
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