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Identification of thresholds for dichotomizing DNA methylation data

DNA methylation plays an important role in many biological processes by regulating gene expression. It is commonly accepted that turning on the DNA methylation leads to silencing of the expression of the corresponding genes. While methylation is often described as a binary on-off signal, it is typic...

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Hlavní autoři: Liu, Yihua, Ji, Yuan, Qiu, Peng
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680080/
https://ncbi.nlm.nih.gov/pubmed/23742247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1687-4153-2013-8
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