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Identification of thresholds for dichotomizing DNA methylation data

DNA methylation plays an important role in many biological processes by regulating gene expression. It is commonly accepted that turning on the DNA methylation leads to silencing of the expression of the corresponding genes. While methylation is often described as a binary on-off signal, it is typic...

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Detalhes bibliográficos
Main Authors: Liu, Yihua, Ji, Yuan, Qiu, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680080/
https://ncbi.nlm.nih.gov/pubmed/23742247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1687-4153-2013-8
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