Monoclonal antibodies to 65kDa glutamate decarboxylase induce epitope specific effects on motor and cognitive functions in rats

BACKGROUND: Stiff Person Syndrome (SPS) is a rare autoimmune movement disorder characterized by the presence of autoantibodies specific to the smaller isoform of glutamate decarboxylase (GAD65). A pathological role of these antibodies has been suggested by their capacity to inhibit GAD65 enzyme acti...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Hampe, Christiane S, Petrosini, Laura, De Bartolo, Paola, Caporali, Paola, Cutuli, Debora, Laricchiuta, Daniela, Foti, Francesca, Radtke, Jared R, Vidova, Veronika, Honnorat, Jérôme, Manto, Mario
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680042/
https://ncbi.nlm.nih.gov/pubmed/23738610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-8-82
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires