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Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing
5-methylcytosine is an epigenetic mark that affects a broad range of biological functions in mammals. The chemically inert methyl group prevents direct labelling for subsequent affinity purification and detection. Therefore, most current approaches for the analysis of 5- methylcytosine still have li...
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| 主要な著者: | , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679896/ https://ncbi.nlm.nih.gov/pubmed/23443545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2527 |
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