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Using a bacteriocin structure to engineer a phage lysin that targets Yersinia pestis

Purified phage lysins present an alternative to traditional antibiotics and work by hydrolyzing peptidoglycan. Phage lysins have been developed against Gram-positive pathogens such as Bacillus anthracis and Streptococcus pneumoniae, where the peptidoglycan layer is exposed on the cell surface. Addit...

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Detalhes bibliográficos
Main Authors: Lukacik, Petra, Barnard, Travis J., Buchanan, Susan K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679646/
https://ncbi.nlm.nih.gov/pubmed/23176506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20120209
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