Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells

Malignant breast tissue contains a rare population of multi-potent cells with the capacity to self-renew; these cells are known as cancer stem-like cells (CSCs) or tumor-initiating cells. Primitive mammary CSCs/progenitor cells can be propagated in culture as floating spherical colonies termed ‘mamm...

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Detalhes bibliográficos
Main Authors: Gong, C, Bauvy, C, Tonelli, G, Yue, W, Deloménie, C, Nicolas, V, Zhu, Y, Domergue, V, Marin-Esteban, V, Tharinger, H, Delbos, L, Gary-Gouy, H, Morel, A-P, Ghavami, S, Song, E, Codogno, P, Mehrpour, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679409/
https://ncbi.nlm.nih.gov/pubmed/22733132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.252
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