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Inhibition of the autophagic flux by salinomycin in breast cancer stem-like/progenitor cells interferes with their maintenance

Breast cancer tissue contains a small population of cells that have the ability to self-renew; these cells are known as cancer stem-like cells (CSCs). We have recently shown that autophagy is essential for the tumorigenicity of these CSCs. Salinomycin (Sal), a K(+)/H(+) ionophore, has recently been...

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Hlavní autoři: Yue, Wen, Hamaï, Ahmed, Tonelli, Giovanni, Bauvy, Chantal, Nicolas, Valérie, Tharinger, Hugo, Codogno, Patrice, Mehrpour, Maryam
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669181/
https://ncbi.nlm.nih.gov/pubmed/23519090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.23997
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