In vivo tissue cholesterol efflux is reduced in carriers of a mutation in APOA1

Atheroprotection by high density lipoprotein (HDL) is considered to be mediated through reverse cholesterol transport (RCT) from peripheral tissues. We investigated in vivo cholesterol fluxes through the RCT pathway in patients with low plasma high density lipoprotein cholesterol (HDL-c) due to muta...

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Autori principali: Holleboom, Adriaan G., Jakulj, Lily, Franssen, Remco, Decaris, Julie, Vergeer, Menno, Koetsveld, Joris, Luchoomun, Jayraz, Glass, Alexander, Hellerstein, Marc K., Kastelein, John J. P., Hovingh, G. Kees, Kuivenhoven, Jan Albert, Groen, Albert K., Turner, Scott M., Stroes, Erik S. G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Patient-Oriented and Epidemiological Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679397/
https://ncbi.nlm.nih.gov/pubmed/23650622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P028449
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