In vivo tissue cholesterol efflux is reduced in carriers of a mutation in APOA1

Atheroprotection by high density lipoprotein (HDL) is considered to be mediated through reverse cholesterol transport (RCT) from peripheral tissues. We investigated in vivo cholesterol fluxes through the RCT pathway in patients with low plasma high density lipoprotein cholesterol (HDL-c) due to muta...

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Hlavní autoři: Holleboom, Adriaan G., Jakulj, Lily, Franssen, Remco, Decaris, Julie, Vergeer, Menno, Koetsveld, Joris, Luchoomun, Jayraz, Glass, Alexander, Hellerstein, Marc K., Kastelein, John J. P., Hovingh, G. Kees, Kuivenhoven, Jan Albert, Groen, Albert K., Turner, Scott M., Stroes, Erik S. G.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2013
Témata:
Patient-Oriented and Epidemiological Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679397/
https://ncbi.nlm.nih.gov/pubmed/23650622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P028449
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