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Hippocampal demyelination and memory dysfunction are associated with increased levels of the neuronal microRNA miR-124 and reduced AMPA receptors

BACKGROUND: Hippocampal demyelination, a common feature of postmortem multiple sclerosis (MS) brains, reduces neuronal gene expression and is a likely contributor to the memory impairment that is found in greater than 40% of individuals with (MS). How demyelination alters neuronal gene expression is...

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書誌詳細
主要な著者: Dutta, Ranjan, Chomyk, Anthony M., Chang, Ansi, Ribaudo, Michael V., Deckard, Sadie A., Doud, Mary K., Edberg, Dale D., Bai, Brian, Li, Michael, Baranzini, Sergio E., Fox, Robert J., Staugaitis, Susan M., Macklin, Wendy B., Trapp, Bruce D
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679350/
https://ncbi.nlm.nih.gov/pubmed/23595422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23860
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