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Hippocampal demyelination and memory dysfunction are associated with increased levels of the neuronal microRNA miR-124 and reduced AMPA receptors
BACKGROUND: Hippocampal demyelination, a common feature of postmortem multiple sclerosis (MS) brains, reduces neuronal gene expression and is a likely contributor to the memory impairment that is found in greater than 40% of individuals with (MS). How demyelination alters neuronal gene expression is...
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主要な著者: | , , , , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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2013
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679350/ https://ncbi.nlm.nih.gov/pubmed/23595422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23860 |
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