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Hippocampal demyelination and memory dysfunction are associated with increased levels of the neuronal microRNA miR-124 and reduced AMPA receptors
BACKGROUND: Hippocampal demyelination, a common feature of postmortem multiple sclerosis (MS) brains, reduces neuronal gene expression and is a likely contributor to the memory impairment that is found in greater than 40% of individuals with (MS). How demyelination alters neuronal gene expression is...
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Główni autorzy: | , , , , , , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
2013
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679350/ https://ncbi.nlm.nih.gov/pubmed/23595422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23860 |
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