Caricamento...

Retained platinum uptake and indifference to p53 status make novel transplatinum agents active in platinum-resistant cells compared to cisplatin and oxaliplatin

Despite the clinical success of platinum-containing drugs in the treatment of solid tumors, acquired resistance remains a major obstacle. We previously identified a group of novel transplanaramine or transplatinum compounds based on distinct activity profiles in the NCI-60 panel. In the present stud...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Murphy, Robert F., Komlodi-Pasztor, Edina, Robey, Rob, Balis, Frank M., Farrell, Nicholas P., Fojo, Tito
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679288/
https://ncbi.nlm.nih.gov/pubmed/22333583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.5.19447
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !