Optimization of Direct Fibroblast Reprogramming to Cardiomyocytes Using Calcium Activity as a Functional Measure of Success

Direct conversion of fibroblasts to induced cardiomyocytes (iCMs) has great potential for regenerative medicine. Recent publications have reported significant progress, but the evaluation of reprogramming has relied upon non-functional measures such as flow cytometry for cardiomyocyte markers or GFP...

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Detalhes bibliográficos
Main Authors: Addis, Russell C., Ifkovits, Jamie L., Pinto, Filipa, Kellam, Lori D., Esteso, Paul, Rentschler, Stacey, Christoforou, Nicolas, Epstein, Jonathan A., Gearhart, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679282/
https://ncbi.nlm.nih.gov/pubmed/23591016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2013.04.004
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