3'-UTR-located inverted Alu repeats facilitate mRNA translational repression and stress granule accumulation

Alu repeats within human genes may potentially alter gene expression. Here, we show that 3′-UTR-located inverted Alu repeats significantly reduce expression of an AcGFP reporter gene. Mutational analysis demonstrates that the secondary structure, but not the primary nucleotide sequence, of the inver...

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Bibliographic Details
Main Authors: Fitzpatrick, Terry, Huang, Sui
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679280/
https://ncbi.nlm.nih.gov/pubmed/22688648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.20827
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