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Inverted Alu repeats unstable in yeast are excluded from the human genome
The nearly one million Alu repeats in human chromosomes are a potential threat to genome integrity. Alus form dense clusters where they frequently appear as inverted repeats, a sequence motif known to cause DNA rearrangements in model organisms. Using a yeast recombination system, we found that inve...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC313988/ https://ncbi.nlm.nih.gov/pubmed/10899135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.14.3822 |
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