Mitochondrial division prevents neurodegeneration

MITOCHONDRIAL DIVISION IS MEDIATED BY THE CONSERVED DYNAMIN-RELATED GTPASE DNM1L/DRP1. DNM1L ASSEMBLES ONTO THE SURFACE OF MITOCHONDRIA AND CONSTRICTS THIS TUBULAR ORGANELLE. ALTERATIONS IN MITOCHONDRIAL DIVISION ARE LINKED TO MANY NEURODEGENERATIVE DISEASES. HOWEVER, THE IN VIVO FUNCTION OF MITOCHO...

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Bibliographic Details
Main Authors: Zhang, Zhongyan, Kageyama, Yusuke, Sesaki, Hiromi
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
Subjects:
Autophagic Punctum
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679233/
https://ncbi.nlm.nih.gov/pubmed/22732519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.21213
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