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Mitochondrial division prevents neurodegeneration
MITOCHONDRIAL DIVISION IS MEDIATED BY THE CONSERVED DYNAMIN-RELATED GTPASE DNM1L/DRP1. DNM1L ASSEMBLES ONTO THE SURFACE OF MITOCHONDRIA AND CONSTRICTS THIS TUBULAR ORGANELLE. ALTERATIONS IN MITOCHONDRIAL DIVISION ARE LINKED TO MANY NEURODEGENERATIVE DISEASES. HOWEVER, THE IN VIVO FUNCTION OF MITOCHO...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679233/ https://ncbi.nlm.nih.gov/pubmed/22732519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.21213 |
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