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PD-L1/B7-H1 regulates the survival, but not the function of CD8(+) T cells in HSV-1 latently infected Trigeminal Ganglia()

Herpes simplex virus type 1 (HSV)-specific CD8(+) T cells provide immunosurveillance of trigeminal ganglion (TG) neurons that harbor latent HSV-1. In C57BL/6 mice the TG-resident CD8(+) T cells are HSV-specific and maintain a 1:1 ratio of cells recognizing an immunodominant epitope on viral glycopro...

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Main Authors: Jeon, Sohyun, St Leger, Anthony J., Cherpes, Thomas L., Sheridan, Brian S., Hendricks, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679223/
https://ncbi.nlm.nih.gov/pubmed/23656736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300582
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