Analysis of Epigenetic Factors in Mouse Embryonic Neural Stem Cells Exposed to Hyperglycemia

BACKGROUND: Maternal diabetes alters gene expression leading to neural tube defects (NTDs) in the developing brain. The mechanistic pathways that deregulate the gene expression remain unknown. It is hypothesized that exposure of neural stem cells (NSCs) to high glucose/hyperglycemia results in activ...

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Hauptverfasser: Shyamasundar, Sukanya, Jadhav, Shweta P., Bay, Boon Huat, Tay, Samuel Sam Wah, Kumar, S. Dinesh, Rangasamy, Danny, Dheen, S. Thameem
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679101/
https://ncbi.nlm.nih.gov/pubmed/23776576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065945
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