Analysis of Epigenetic Factors in Mouse Embryonic Neural Stem Cells Exposed to Hyperglycemia

BACKGROUND: Maternal diabetes alters gene expression leading to neural tube defects (NTDs) in the developing brain. The mechanistic pathways that deregulate the gene expression remain unknown. It is hypothesized that exposure of neural stem cells (NSCs) to high glucose/hyperglycemia results in activ...

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Main Authors: Shyamasundar, Sukanya, Jadhav, Shweta P., Bay, Boon Huat, Tay, Samuel Sam Wah, Kumar, S. Dinesh, Rangasamy, Danny, Dheen, S. Thameem
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679101/
https://ncbi.nlm.nih.gov/pubmed/23776576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065945
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