Imaging Proteolytic Activity in Live Cells and Animal Models

In addition to their degradative role in protein turnover, proteases play a key role as positive or negative regulators of signal transduction pathways and therefore their dysregulation contributes to many disease states. Regulatory roles of proteases include their hormone-like role in triggering G...

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Główni autorzy: Galbán, Stefanie, Jeon, Yong Hyun, Bowman, Brittany M., Stevenson, James, Sebolt, Katrina A., Sharkey, Lisa M., Lafferty, Michael, Hoff, Benjamin A., Butler, Braeden L., Wigdal, Susan S., Binkowski, Brock F., Otto, Paul, Zimmerman, Kris, Vidugiris, Gediminas, Encell, Lance P., Fan, Frank, Wood, Keith V., Galbán, Craig J., Ross, Brian D., Rehemtulla, Alnawaz
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2013
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679058/
https://ncbi.nlm.nih.gov/pubmed/23776643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066248
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